Crispr Python Packages

mgsurve

Python package to optimize mosquito traps' positioning in field trials.

monet-mgdrive

MoNeT python package for MGDrivE data analysis

spacr

Spatial phenotype analysis of crisp screens (SpaCr)

screenpro2

Flexible analysis of high-content CRISPR screening

diced

A Rust reimplementation of the MinCED method for identifying CRISPRs in full or assembled genomes.

cy

Python module to analyse CRISPR-based libraries

crispyx

crispyx is a Python package for scalable CRISPR and Perturb-seq screen analysis on disk-backed AnnData files. It provides streaming quality control, normalization, pseudobulk aggregation, and differential expression without loading the full count matrix into memory.

spacr-nightly

Spatial phenotype analysis of crisp screens (SpaCr)

crispio

Designing CRISPR-Cas guide RNAs in bacteria.

cctyper

CRISPRCasTyper: Automatic detection and subtyping of CRISPR-Cas operons

crisprhawk

Variant- and Haplotype-aware CRISPR guide design toolkit

genome-atlas

Programmable genome‑writing knowledge graph and GNN toolkit for DNA‑modifying enzymes, combining CRISPR/CAST/Fanzor annotations with ESM‑2 embeddings, GraphSAGE/GAT link prediction, and an editor‑selection API for gene‑editing use cases.

genet

Python library for genome editing, CRISPR gRNA design and prediction

crispresso

Software pipeline for the analysis of CRISPR-Cas9 genome editing outcomes from sequencing data

vintools

Michael Vinyard's utilities

berets

Tools for analyzing CRISPR data with REPorter edits

fba

Tools for single-cell feature barcoding analysis

crispr-bean

Base Editor screen analysis with guide Activity Normalization

py-crispr-analyser

Analyse a genome for CRISPRs and off-targets

beditor

A computational workflow for designing libraries of guide RNAs for CRISPR base editing

pycroquet

python Crispr Read to Oligo QUantification and Evaluation Tool

synthego-ice

Synthego ICE - Inference of CRISPR Editing software

pool-sharq

pool-sharq: python interface for Broad Institute GPP's poolq software.

ogilo-array

⛓️ Automating construction of oligo library sequences for oligo array synthesis.