PyRank
pysam-developers

pysam

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.
PyPI GitHub Verified repo
No known security advisories. The current version has no OSV.dev malware reports and no critical or high-severity vulnerabilities.

pysam has 1.2M monthly downloads and 896 GitHub stars. Version 0.24.0 supports Python 3.8+, first published in 2011.

It is actively maintained under a permissive license, last released in Apr 2026.

It is used by 687 tracked packages, including pybedtools, biocommons-seqrepo and crested.

GitHub topics include bioinformatics, ngs and htslib.

Shared Repository
This package shares its GitHub repository (pysam-developers/pysam) with 2 other packages. Stars, forks, and other GitHub metrics reflect the entire repository.
Downloads
Day
35.6K
Week
265.7K
Month
1.2M
Stars
896
Forks
298
Issues
243
Version
0.24.0

Package Insights

What's this?
Score breakdown - each component scores 0-100, weighted by percentage
Maintenance
90
Popularity
66
Adoption
70
Community
100
Provenance
100
How the maintenance status was determined
Last commit
13 days ago
Monthly downloads
1,214,055
• Active
Activity within 30 days
Stable
Activity within 31-180 days
Minimal
Activity within 181-365 days, or no activity data
At Risk
No activity for > 365 days, but > 10,000 monthly downloads
Archived
Repository flagged as archived on GitHub
How the popularity category was determined
Monthly downloads
1,214,055
Stars
896
Stars per 1k downloads
0.74
Industry Standard
> 10,000,000 monthly downloads
Hidden Gem
< 0.5 stars per 1k downloads and > 100,000 monthly downloads
Community Favorite
> 5 stars per 1k downloads
• Rising Star
Balanced ratio of stars to downloads
Unknown
Fewer than 1,000 monthly downloads, or no star data
How download momentum is calculated
Week daily avg
37,963
Month daily avg
40,468
Momentum
-6.2%
((week_daily_avg - month_daily_avg) / month_daily_avg) * 100
Python version support tiers
requires_python
>=3.8
Cutting Edge
Minimum supported version is 3.12 or newer
Modern
Minimum supported version is 3.9, 3.10, or 3.11
• Legacy
Supports 3.8 or older (or Python 2)
Unknown
No requires_python specified or unparseable
License categories
License
MIT License
• Permissive
MIT, Apache, BSD, ISC, Unlicense, CC0, etc.
Copyleft
GPL, LGPL, AGPL, MPL, EPL, etc.
Proprietary
Commercial, all rights reserved, custom EULAs
Unknown
No license specified, or none of the above match
How the release cadence was determined
Last release
70 days ago
Total releases
48
Releases/year
3.1
Rapid
Last release within 365 days and > 12 releases/year
• Regular
Last release within 365 days
Slow
Last release 366-730 days ago
Stalled
Last release > 730 days ago, or no releases
Unknown
No usable release date available
How contributor risk was determined
Contributors
101
Monthly downloads
1,214,055
High Load
≤ 2 contributors and ≥ 50,000 monthly downloads
Moderate Load
< 10 contributors and ≥ 500,000 monthly downloads
Low Load
< 25 contributors and ≥ 5,000,000 monthly downloads, or sole maintainer with ≥ 10,000 monthly downloads
• Balanced
Enough contributors for the package's popularity
Unknown
No contributor data available
Engagement
80
 
Issue Burden
271.2
per 1k stars
Discussions
0.0
per 1k stars
Fork Ratio
33.9%
contrib / forks
Stale Release
No
 
PR Velocity
Quiet
 

Weekly Downloads

GitHub Stars

Not all downloads include detailed metadata. Breakdowns reflect the subset that does.

Downloads by OS

Linux 26.2K
macOS 1.1K
Windows 128

Python Versions

3.12
47.1% 12.3K
3.10
27.7% 7.3K
3.11
14.9% 3.9K
3.13
7.1% 1.9K
3.8
3.2% 831

Top Countries

1. US US
23.6K
2. CN CN
1.2K
3. SG SG
930
4. DE DE
624
5. ID ID
593
6. GB GB
249
7. IE IE
228
8. HK HK
205
9. FI FI
149
10. NL NL
80
GitHub Topics
Tags from the package's GitHub repository describing what it does.

Package Information

License
MIT License
First Release
February 11, 2011
Last Release
2 months ago
Last Commit
2 weeks ago
Latest Version
0.24.0
Total Releases
48
Contributors
101
Open PRs
24
Archived
No
Author
Andreas Heger
Wheels
cp27 cp310 cp311 cp312 cp313 cp314 cp34 cp37 cp38 cp39
Tracking Since
January 6, 2026
Data Updated
July 5, 2026
Data Freshness
Fresh

Links