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Python Bindings Packages

Python packages with the GitHub topic python-bindings. Sorted by relevance, with stars and monthly downloads.
althonos
pyhmmer

Cython bindings and Python interface to HMMER3.

3.9M 165 17
pyimgui
imgui

Cython-based Python bindings for dear imgui

120K 2K 187
fastobo
fastobo

Faultless AST for Open Biomedical Ontologies in Python.

107K 33 4
althonos
pyfamsa

Cython bindings and Python interface to FAMSA, an algorithm for ultra-scale multiple sequence alignments.

39K 45 4
jd-boyd
python-lzo

Python bindings for the LZO data compression library

24K 84 46
carbonblack
cbapi

Carbon Black API - Python language bindings

17K 146 87
ChrisTimperley
comby

Python bindings for Comby

15K 13 2
1minds3t
uv-ffi

Persistent in-process execution engine for uv — internal dependency of omnipkg

14K 4 0
commx
rrdtool

Python bindings for rrdtool

12K 82 28
stanislavulrych
tempo-api-python-client

Python bindings for Tempo - https://apidocs.tempo.io/

12K 36 23
borco
pyside6-scintilla

PySide6 bindings for Scintilla

10K 2 0
dartsim
dartpy

Research-focused C++23 physics engine for robotics, animation, and machine learning, with Python bindings

10K 1K 301
DanMeon
rhwp-python

PyO3 Python bindings for rhwp — parser and renderer for HWP/HWPX documents (Korean Hancom word processor format)

7K 10 4
althonos
pyopal

Cython bindings and Python interface to Opal, a SIMD-accelerated database search aligner.

6K 11 1
HaarigerHarald
geant4-pybind

Alternative Python bindings for Geant4

6K 45 8
VolkovIlia
semiflow-pde

Fast no_std Rust library for evolution equations and PDEs via Chernoff approximation of operator semigroups — heat, Schrödinger, diffusion, graph & manifold operators. Bindings for C, Python, and WebAssembly.

5K 2 0
bertiniteam
pybertini

Bertini 2: The redevelopment of Bertini in C++ and Python.

5K 115 39
vrasneur
pyfasttext

Yet another Python binding for fastText

5K 224 29
RustedBytes
fast-h2m

a fork of html-to-markdown with speed enhancements

5K 10 1
oldnordic
sqlitegraph

Embedded graph database on SQLite — HNSW vector search, Cypher-like queries, graph algorithms (BFS, A*, SCC, dominance), ACID + WAL + MVCC delta log, Python bindings, Native V3 CSR backend.

5K 12 1
sbrodehl
pypublicdecompwt

Python bindings for EUMETSAT's PublicDecompWT

4K 3 1
zentrum-lexikographie
sfst-transduce

Python bindings for SFST focusing on transducer usage

4K 4 0
pharmai
plip

Protein-Ligand Interaction Profiler - Analyze and visualize non-covalent protein-ligand interactions in PDB files according to 📝 Schake, Bolz, et al. (2025), https://doi.org/10.1093/nar/gkaf361

4K 696 139
bertiniteam
bertini2

Bertini 2: The redevelopment of Bertini in C++ and Python.

4K 115 39
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