Automated design and scoring engine for IS110-family bridge recombinase variants, nominating 1,029 candidates via an 8-axis PenScore over pre-registered predictions.
Multi-axis scoring framework that ranks programmable genome editors across eight orthogonal axes into a single PenScore to guide experimental design and benchmarking.
Two-tier classifier for the catalytic mechanism of programmable genome-writing enzymes, with a biochemical gate that correctly labels IS110-family composite recombinases.
