Crispr Cas9 Python Packages

screenpro2

Flexible analysis of high-content CRISPR screening

crispresso

Software pipeline for the analysis of CRISPR-Cas9 genome editing outcomes from sequencing data

cctyper

CCTyper: Automatic detection and subtyping of CRISPR-Cas operons

cassiopeia-lineage

A Package for Cas9-Enabled Single Cell Lineage Tracing Tree Reconstruction

crisprzip

A kinetic model of CRISPR-Cas target recognition.

pycrispr

Pip package for CRISPR-Cas9 screen analysis

genome-atlas

Knowledge graph and GNN benchmark for programmable genome-writing enzymes, with ESM-2 embeddings, GraphSAGE/GAT link prediction, and an editor-selection API.

crispr-cas9

NGS data analysis scripts for HBV elimination research group

pen-score

Multi-axis scoring framework that ranks programmable genome editors across eight orthogonal axes into a single PenScore to guide experimental design and benchmarking.

mech-class

Two-tier classifier for the catalytic mechanism of programmable genome-writing enzymes, with a biochemical gate that correctly labels IS110-family composite recombinases.

acrcasppi-ml

Prediction of protein-protein interaction between anti-crispr protein (acr) and CRISPR-associated (cas) protein using machine learning algorithm

biodive

A reference-free statistical approach to diversity-generating & mobile genetic element discovery

crispr-da

CRISPR-Cas9 sgRNA design across many genomes

crispr-cats

Comparing Cas Activities by Target Superimposition (CATS)