Computational Neuroscience Python Packages

efel

Electrophys Feature Extraction Library

brian2

Brian is a free, open source simulator for spiking neural networks.

bluepyopt

Blue Brain Python Optimisation Library

bluepyefe

BluePyEfe: Blue Brain Python E-feature extraction

hypercube-hopfield

Modern Hopfield associative memory on a hypercube graph. Sparse local-attention retrieval with exponential capacity. C++23 and Python SDKs.

spikegen

Generate spike trains (Poisson, gamma renewal, regular, inhomogeneous) in pure Python with zero dependencies.

spikedist

Spike-train distance metrics (Victor-Purpura, van Rossum) in pure Python with zero dependencies.

driada

Dimensionality Reduction for Integrated Activity Data Analysis

cleosim

Closed-Loop, Electrophysiology, and Optophysiology experiment simulation testbed for mesoscale neuroscience

tklfp

Lightweight package for computing the kernel LFP approximation from Teleńczuk et al., 2020

ngclearn

NGC-Learn: Computational Neuroscience and NeuroAI in Python

spikestats

Spike-train statistics (firing rate, CV, CV2, Fano factor, local variation Lv and LvR) in pure Python with zero dependencies.

wslfp

Weighted Sum Local Field Potentials - Implementation of the proxy method for point neurons from Mazzoni, Lindén et al., 2015

neurotune

Package for fitting/optimization of NeuroML models

ratinabox

A python package for simulating movement and spatial cell types (e.g. place cells, grid cells) in continuous environments.

neurolib

Easy whole-brain modeling for computational neuroscientists 🧠💻👩🏿‍🔬

brian2cuda

A brian2 extension to simulate spiking neural networks on GPUs

neuromodels

Computational neuroscience models and model tools

pointprocess

A C++ Library for Point Process Analysis

biosimulators-pyneuroml

pyNeuroML simulation program via BioSimulators-compliant command-line interface and Docker container

foveatorch

👀🔥 Differentiable foveated vision for Deep Learning methods

functional-connectivity

Sensing the functional connectivity of the brain

esi-syncopy

Systems Neuroscience Computing in Python: user-friendly analysis of large-scale electrophysiology data

openretina

Collaborative retina modelling across datasets and species.