Computational Neuroscience Python Packages

efel

Electrophys Feature Extraction Library

brian2

Brian is a free, open source simulator for spiking neural networks.

bluepyopt

Blue Brain Python Optimisation Library

bluepyefe

BluePyEfe: Blue Brain Python E-feature extraction

neurolib

Easy whole-brain modeling for computational neuroscientists 🧠💻👩🏿‍🔬

driada

Dimensionality Reduction for Integrated Activity Data Analysis

ngclearn

Simulation software for building and analyzing computational neuroscience models, brain-inspired computing systems, and NeuroAI agents.

brian2cuda

A Brian2 extension to simulate spiking neural networks on GPUs

ratinabox

A python package for simulating movement and spatial cell types (e.g. place cells, grid cells) in continuous environments.

cleosim

Closed-Loop, Electrophysiology, and Optophysiology experiment simulation testbed for mesoscale neuroscience

hypercube-hopfield

Modern Hopfield associative memory on a hypercube graph. Sparse local-attention retrieval with exponential capacity. C++23 and Python SDKs.

pointprocess

A C++ Library for Point Process Analysis

biosimulators-pyneuroml

BioSimulators-compliant command-line interface to the jNeuroML/pyNeuroML, NEURON, and NetPyNe simulation programs.

neurotune

Package for fitting/optimization of NeuroML models

neuromodels

Computational neuroscience models and model tools.

foveatorch

Differentiable foveated vision for Deep Learning methods

zpe-neuro

ZPE-Neuro V0.0: DETERMINISTIC NEURAL SIGNAL CODEC: Extracellular Spikes | Neuropixels | DANDI-Anchored | IBL Validated | Spike Train Transport

tklfp

Lightweight package for computing the kernel LFP approximation from Teleńczuk et al., 2020

openretina

Open source retina model architectures and training setups

functional-connectivity

Sensing the functional connectivity of the brain

wslfp

Weighted Sum Local Field Potentials - Implementation of the proxy method for point neurons from Mazzoni, Lindén et al., 2015

sim2bids

App to preprocess and convert simulation data

esi-syncopy

Systems Neuroscience Computing in Python: user-friendly analysis of large-scale electrophysiology data

neurosig-analyseur

analyseur is a module for analyzing (potentially) myriad models developed (or involved) in Dr. Benoît Girard’s lab