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Blockchain Python Packages

Python packages with the GitHub topic blockchain. Sorted by monthly downloads, with stars and forks.
kevinheavey
solders

A high-performance Python toolkit for Solana, written in Rust

1.7M 449 53
michaelhly
solana

Solana Python SDK

1.2M 1K 340
Chia-Network
chiapos

Chia Proof of Space library

319K 269 294
StellarCN
stellar-sdk

Stellar client library for the Python language

233K 368 177
RaoFoundation
bittensor

Bittensor

222K 391 350
fireblocks
fireblocks-sdk

DEPRECATED — use the fireblocks package. End-of-life Nov 1, 2026.

176K 53 45
polkascan
scalecodec

Python SCALE-Codec

166K 59 56
polkascan
substrate-interface

Python Polkadot SDK

128K 256 124
tintinweb
evmdasm

A lightweight ethereum evm bytecode instruction registry, disassembler and evmcode manipulation library

106K 61 13
RaoFoundation
bittensor-core

Bittensor

105K 391 350
tintinweb
ethereum-dasm

An ethereum evm bytecode disassembler and static/dynamic analysis tool

105K 223 40
kevinheavey
anchorpy

The Python Anchor client.

98K 279 76
XRPLF
xrpl-py

A Python library to interact with the XRP Ledger (XRPL) blockchain

94K 246 137
yungwine
pytoniq-core

TON Blockchain SDK with native ADNL protocols implementations

81K 135 57
Certora
certora-cli

The Certora Prover is the state-of-the-art security tool for automated formal verification of smart contracts running on EVM-based chains, Solana and Stellar

60K 337 48
fetchai
cosmpy

A Python client library for interacting with blockchains based on the Cosmos-SDK

57K 149 84
blockfrost
blockfrost-python

Python 3 SDK for the Blockfrost.io API.

57K 75 18
Python-Cardano
pycardano

A lightweight Cardano library in Python

54K 253 92
serengil
lightecc

A Lightweight Elliptic Curve Cryptography Arithmetic Library For Python with Support for Prime and Binary Fields

54K 10 2
ConsenSys
mythril

Mythril is a symbolic-execution-based securty analysis tool for EVM bytecode. It detects security vulnerabilities in smart contracts built for Ethereum and other EVM-compatible blockchains.

46K 4K 820
FrankC01
pysui

SUI Python Client SDK

42K 212 62
yungwine
pytoniq

TON Blockchain SDK with native ADNL protocols implementations

29K 135 57
cdklabs
cdklabs-cdk-hyperledger-fabric-network

CDK construct to deploy a Hyperledger Fabric network running on Amazon Managed Blockchain

27K 9 7
BobTheBuidler
eth-portfolio-temp

Use eth-portfolio to output information about a wallet or collection of wallets in a streamlined, speed-optimized way.

22K 15 6
    • Original data from PyPI, GitHub, and OSV; downloads served through ClickHouse
    • Sources & methodology