Antibody Python Packages

arda-mapper

High-throughput mapping and domain partitioning of antigen receptor sequences

vdjtools

Analysis of immune repertoire sequencing results

immunum

A high-performance antibody and TCR sequence numbering tool for Rust, Python, Polars and JS/TS.

mirpy-lib

Machine learning for Immune Repertoires

sapiens

Sapiens is a human antibody language model based on BERT.

tidytcells

Standardise TR/MH/IG data

migec

An UMI-tagged sequencing swiss-knife. Built for amplicon sequencing of immune repertoires, ctDNA and rare mutations, single-cell sequencing.

abpytools

Python package for analysis of antibody heavy and light chains

alignair

Deep-learning V(D)J aligner for BCR and TCR sequences. A single model predicts V/D/J allele calls, segment boundaries and the junction, with AIRR-format output. Published in Nucleic Acids Research (2025).

antifold

Improved antibody structure-based design using inverse folding

ligo

LIgO is a tool for simulation of adaptive immune receptors and repertoires.

protstruc

Protein structure handling in Python made easy.

ablanx

JAX/Flax port of AbLang2's AbRep encoder: differentiable antibody language-model embeddings and per-block attention, loading the original weights unchanged.

igfold-pytorch

Unofficial re-implementation of IgFold, a fast antibody structure prediction method, in PyTorch.

jaxfvld

Small, fast, fully differentiable antibody Fv structure predictor in JAX. ~0.76M parameters, matches IgFold on CDR-H3, folds an Fv in ~0.8s on CPU.

deepab-pytorch

An unofficial re-implementation of DeepAb, an interpretable deep learning model for antibody structure prediction.