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Ai Assistant Python Packages

Python packages with the GitHub topic ai-assistant. Sorted by monthly downloads, with stars and forks.
CopilotKit
copilotkit

The Frontend Stack for Agents & Generative UI. React, Angular, Mobile, Slack, and more. Makers of the AG-UI Protocol

328K 38K 5K
gptme
gptme

Your agent in your terminal, equipped with local tools: writes code, uses the terminal, browses the web. Make your own persistent autonomous agent on top!

38K 4K 450
szczyglis-dev
pygpt-net

Desktop AI Assistant powered by GPT-6, GPT-5, Gemini, Claude, Grok, Ollama, DeepSeek, Perplexity, and more - chat, agents, tools, MCP, plugins, RAG, vision, voice, image and video generation, speech synthesis and speech recognition, web search, memory, presets, canvas, assistants, themes, computer use. Windows, Linux, and Mac.

31K 2K 351
sonic182
minibot

Your personal AI assistant - self-hosted, containerized, and intentionally opinionated.

19K 4 0
jeff-nasseri
mcp-server-mikrotik

MCP server for Mikrotik

18K 299 67
saigontechnology
agentcrew-ai

Chat application with multi-agents system supports multi-models and MCP

10K 217 43
CorvinLabs
corvinos

Self-hosted agentic OS — a Vibe-Engineering platform for Builders. Connect Claude Code Agent to Discord, Telegram, WhatsApp, Slack & Email. EU AI Act 2026 & GDPR compliance by architecture.

10K 17 3
epinethrone
icloud-mcp-server

Self-hosted MCP server that connects Claude to Apple iCloud: Mail, Calendar, Contacts, Reminders, Notes and iCloud Drive. Single-owner OAuth, approval-first, built for prompt-injection safety.

6K 4 3
mariusei
scantool

MCP server for code structure analysis across 20+ languages. Tree-sitter powered. Works with Claude Code and Claude Desktop.

5K 3 0
ziya-ai
ziya

Self-hosted AI technical workbench. Visual, persistent, multi-stream. Development, architecture, and operational analytics without losing context.

5K 39 21
gptme
gptme-acp

Your agent in your terminal, equipped with local tools: writes code, uses the terminal, browses the web. Make your own persistent autonomous agent on top!

5K 4K 450
moorcheh-ai
moorcheh-sdk

Python SDK for interacting with the Moorcheh Semantic Search API v1. Moorcheh provides ultra-fast, highly accurate vector similarity search and analysis capabilities based on information-theoretic principles.

4K 52 6
UClone-AI
uclone-x

Open-source, self-hosted AI agents on your own machine — multi-agent group chat with memory, file tools, MCP and local image generation. Works with Ollama, Gemini, Claude and OpenAI.

3K 0 0
vintasoftware
django-ai-assistant

Integrate AI Assistants with Django to build intelligent applications

3K 431 40
mosquito
axio

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
mosquito
axio-transport-openai

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
mosquito
axio-tools-mcp

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
mosquito
axio-tui

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
roampal-ai
roampal

Outcome-based persistent memory MCP server for Claude Code and OpenCode. Good advice promoted, bad advice demoted. pip install roampal.

2K 54 8
cremind-ai
cremind

Self-hosted personal AI assistant: multi-profile agents with any LLM, MCP tools, skills, automations and chat channels. Web UI, desktop app and CLI.

2K 0 0
mosquito
axio-tools-docker

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
mosquito
axio-tools-local

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
mosquito
axio-transport-codex

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
mosquito
axio-tui-guards

Axio — Asynchronous eXtensible Intelligent Orchestration. A minimal, streaming-first, protocol-driven foundation for LLM-powered agents.

2K 1 2
    • Original data from PyPI, GitHub, and OSV; downloads served through ClickHouse
    • Sources & methodology